nlmixr2 2.0.8 log-likelihood

I am pretty excited abut the new nlmixr2 release (2.0.8). When I joined the the nlmixr2 team, I wanted to do a fancy heavy tailed, skewed model in an open source tool so I could figure out how to do even more with it. With this release, it is possible to do a heavy tailed (t-distribution dt()) skewed (coxBox(lambda)) distribution: my old wish is now possible with focei! A few other things that people may be interested in are:

By Matt Fidler and the nlmixr2 Development Team in nlmixr2

October 24, 2022

rxode2 2.0.9/2.0.10

rxode2 2.0.9 has been released, and rxode2 2.0.10 will be released soon! I want to personally thank all those who have submitted issues, and helped with the development. Without the support rxode2 wouldn’t be the tool it is today. This is the first CRAN-visible release since rxode2 2.0.7 and I would like to highlight a few new interesting features: ‘rxode2’ can now have more flexible model functions The key features are:

By Matthew Fidler in rxode2

October 19, 2022

mrgsolve vs rxode2

mrgsolve vs rxode2 One of the most common questions I get is, “What are the differences between mrgsolve (1) and rxode2?”. The most common reasons for this question are: I really don’t know what tool to use, what are the advantages of each? I really like one of the tools (either mrgsolve or rxode2) and I want to let my colleagues know how nice my favorite tool is. I am not really the best person to answer this question since I am most familiar with rxode2 and can’t answer all the questions about mrgsolve.

RxODE and rxode2

RxODE vs rxode2 Since rxode2 came out recently, I am getting many questions about what is the difference between rxode2 and RxODE. I think the biggest reason for the question is – is this update going to break all the nice things I already do with RxODE? Or maybe why should I bother to change? I feel the same way when I have big changes in things I use. For me, I love the ability to pipe and change data with the tidyverse, and similar tools, but hate when they change things that affect my code.

By Matthew Fidler in rxode2

October 12, 2022

nlmixr2 is here

Over the past half year, a lot of changes have been happening behind the scenes, and the time has finally come to reveal them! nlmixr2 nlmixr2 will be the version in active development going forward, taking over from nlmixr, starting with the current CRAN version, 2.0.6. Our new home on GitHub is here, and on CRAN, we’re here. The reasons for the name and format change are many, but most importantly, we’ve taken this step to improve overall user experience and to help us maintain the project more effectively.

By the nlmixr2 Development Team in nlmixr2

June 8, 2022